Who’ll be Canada’s next Chief Public Health Officer? You should care by Lyne Filiatrault Arijit Chakravarty David Fisman, April 24, 2025
@TRyanGregory:
NOT Bonnie Henry. No. Just NO.
@Mtlman_1:
She’s a clown and I hope no party wants her. Bonnie would fit in with the Trump administration.
@arijitchakrav:
Exemplary coverage from @NatGeo on the rise in heart attacks.
Gives fair weight to COVID infections as one of the causes. (The “up to 3yrs” framing is wrong, of course. The correct interpretation of the findings in those studies is “for at least 3yrs”.)
Why heart attacks are rising in young adults—and what to watch out for, Research shows that heart attacks are becoming more prevalent among adults younger than 50—and the outcomes are worse for women. The good news is we know how to prevent them by Katie Camero, April 23, 2025, National Geographic
Despite declines among older adults, the proportion of heart attacks among younger adults is increasing across the globe—an alarming trend that many doctors who spoke to National Geographic consider a public health emergency. (Young adults are loosely defined as those between 20 to 50 years old.)
Mounting evidence also shows that more young adults are experiencing all kinds of heart problems compared to decades past, and that worsening lifestyle habits—namely, poor diet and lack of exercise—are to blame.
And some research suggests that COVID infections are adding insult to injury.
(It’s not just heart attacks. Colon cancer is rising among young adults.)
Recent events have underscored these concerns. In 2024, a healthy 38-year-old made headlines after he had a heart attack and collapsed while running the New York City Triathlon, despite having no known risk factors. And in 2023, fans were left stunned after 18-year-old Bronny James, the oldest son of NBA star LeBron James, collapsed after going into cardiac arrest during basketball practice at the University of Southern California. (He has since resumed playing following surgery to treat what his family said was a congenital heart defect.)
The event, and several others like it, raises questions more broadly about cardiovascular health and young people.
“Young individuals are not immune from cardiac arrest or heart attack, yet many think that this is still a disease of older folks,” says Ron Blankstein, senior preventive cardiologist at Brigham and Women’s Hospital and professor of medicine at Harvard Medical School in Boston. “But the really important thing for young individuals to know is that cardiovascular disease, for the most part, can be prevented if you take the right steps.”
Heart attacks on the rise in younger adults
Heart attacks, also called myocardial infarctions, occur when blood flow into the heart is partially or completely blocked. Common symptoms include chest pain or discomfort; pain that radiates into the jaw, neck, back or arms; shortness of breath; and feeling weak or faint.
According to the National Center for Health Statistics, 0.3 percent of adults in the U.S. ages 18 to 44 had a heart attack in 2019 compared to 0.5 percent in 2023. That’s a 66 percent increase over four years. Meanwhile, heart attacks decreased among all other age groups over the same period.
A study of more than 2,000 young adults admitted for heart attack between 2000 and 2016 in two U.S. hospitals found that 1 in 5 were 40 years old or younger—and that the proportion of this group has been increasing by 2 percent each year for the last decade.
The study, published in 2019 in the American Journal of Medicine, also found that people ages 40 or younger who have had a heart attack are just as likely as older adults to die from another heart attack, stroke, or other reason.
In fact, increases in heart disease among younger adults between 2020 and 2021 were responsible for more than 4 percent of the declines in U.S. life expectancy in that year, according to a 2023 editorial published in JAMA Network.
Not to mention, more young adults are dying of heart failure, which is when your heart can’t pump enough blood to meet your body’s needs. (Heart failure can be caused by anything that weakens the muscle, such as coronary heart disease, high blood pressure, irregular heartbeat, and heart attacks.) A study published last year in JAMA Cardiology found that deaths among people aged 45 and younger from 2012 to 2021 were responsible for completely reversing 13 years’ worth of declines in heart failure-related mortality from 1999 to 2012.
Cardiac arrest, however, is a different situation: It occurs when the heart experiences an electrical malfunction and suddenly stops beating. Because cardiac arrest can be caused by several conditions—like cardiomyopathy (thickened heart muscle), heart failure, arrhythmias (irregular heartbeat), and heart attacks—it’s difficult for doctors to study and determine whether it’s becoming more common in young adults.
Who is most at risk?
The problem isn’t uniquely American. Research shows that adults in Pakistan and India, for example, are also experiencing heart attacks at younger ages. “Cardiovascular disease doesn’t know international boundaries,” Blankstein said, “and neither do the risk factors.”
And though heart attacks typically strike men more often than women, recent studies have suggested that more younger women are experiencing heart attacks compared to younger men—and that their outcomes are worse.
A 2018 investigation published in the journal Circulation found that the overall proportion of heart attack hospitalizations among people ages 35 to 54 in four regions of the U.S. increased from 27 percent in 1995-99 to 32 percent in 2010-14. The largest increase occurred in young women (21 percent to 31 percent) compared to young men (30 percent to 33 percent).
The young women in the study were more often Black and had a history of high blood pressure, diabetes, chronic kidney disease, and prior stroke.
Studies have found that clinicians are more likely to dismiss symptoms and underdiagnose certain risk factors in women, and are less likely to prescribe them medications to help manage their risks.
Overall, women are more likely than men to die from a heart attack and develop heart failure in the five years after their hospitalization, according to a 2024 report by the McKinsey Health Institute and the American Heart Association. Today, cardiovascular disease remains the leading cause of death in women in the U.S.
What are the biggest risk factors?
The majority of research shows that more people, particularly those of diverse racial and ethnic backgrounds, are developing risk factors for heart disease at younger ages—and that most of the young, seemingly healthy people who have a heart attack almost always have at least one underlying condition.
The biggest risk factors are high blood pressure, diabetes, high cholesterol, and obesity, all of which can clog and damage the arteries and blood vessels that carry oxygen-rich blood to the heart.
While some of these conditions may be genetic, more often they’re brought on by years of unhealthy habits like poor diet and a sedentary lifestyle that typically begin early in childhood, says Eugene Yang, a preventive cardiologist and former chair of the American College of Cardiology Prevention of Cardiovascular Diseases Council.
COVID, on the other hand, appears to have a more immediate impact on cardiovascular health. A 2022 study published in the Journal of Medical Virology found that heart attack deaths increased by 14 percent within the first year of the pandemic. The greatest increase was found among adults aged 25 to 44. More recent research suggests that COVID can increase heart attack risk for up to three years post-infection among some young unvaccinated adults. On the flip side, COVID vaccines have been found to lower the risk of heart attacks among all adults.
(How COVID-19 harms the heart.)
COVID is known to activate inflammatory responses in the body and make blood thicker and stickier, Yang said, which can make infected people more susceptible to blood clots that can clog arteries and lead to heart attack. However, it’s still not clear why younger adults appear to be more vulnerable to COVID’s cardiovascular complications.
Other factors like tobacco, cocaine,marijuana, and alcohol use have been associated with increased risks of heart attack in younger adults too. Research also shows that racism and discrimination, such as segregated neighborhoods and workplace inequality, can have major impacts on cardiovascular health and access to quality care, which can explain why young people of color face greater risks for heart problems.
Young adults aren’t aware of their risks
Yet, most young adults aren’t concerned. A 2023 survey by The Ohio State University Wexner Medical Center found that 47 percent of people under age 45 don’t think they’re at risk for heart disease; a third of all adults surveyed said they wouldn’t confidently know whether they were having a heart attack.
Similarly, just half of 3,500 younger adults who had significant risk factors believed they were at risk for heart disease before their heart attack occurred; even fewer reported that their doctors told them they were at risk, especially women.
Getting younger adults to care about heart health is a unique challenge, experts say; they’re busy building families and careers and are the least likely age group to have health insurance.
But it’s not all their fault. The health care system isn’t designed to effectively evaluate and treat younger adults with heart disease, Blankstein said, fueling a bias among clinicians that younger patients are at low risk.
Since 2013, the most widely used “risk calculator” developed by the American Heart Association, for example, only assessed risks for those ages 40-79. It wasn’t until 2023 that the new PREVENT calculator included people ages 30 and older.
Further, most young adults who had a heart attack would not have been eligible for cholesterol treatment under current guidelines before their heart attack occurred; women face even lower eligibility compared with men, despite similar risk factors.
How to reduce risks of heart attack
Early prevention is key. The longer you live with risk factors, the greater your chances of developing heart disease and experiencing worse outcomes later in life, especially if left untreated.
“Take a good look at your risk factors,” says Mariell Jessup, chief science and medical officer with the AHA, “and then develop a plan about how you can tackle one or more of those.”
The AHA recommends following “Life’s Essential 8”: key measures that, if practiced, can improve and maintain your cardiovascular health. These include a healthy diet, regular physical activity, no tobacco smoking, and sufficient sleep, as well as managing your weight, cholesterol, blood sugar, and blood pressure.
A 2024 study published in the AHA journal found that adults ages 21-27 who followed these guidelines more closely had thinner, less stiff, and overall healthier carotid artery walls (the major blood vessels in your neck) compared to those who didn’t follow them as well. In other words, they had lower risks for cardiovascular disease and heart attacks.
“Young adulthood is a phenomenal opportunity for prevention of cardiovascular disease, which goes hand in hand with overall health,” says John Wilkins, associate professor of medicine in cardiology at the Northwestern University Feinberg School of Medicine. “The better job we can do at getting young adults at these optimal levels, the greater chance they have at a longer health span.”
Editor’s note: This story originally published on August 4, 2023. It has been updated with new research.
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2025:
@Daniel_E_Park:
Large study in children and adolescents shows that SARS-CoV-2 infection is linked with long term cardiovascular complications.And BC’s evil “be kind” and “wash your hands” (even though the virus is airb0rne) social murderer Dr. Bonnie Henry told the public kids didn’t get COVID and didn’t take it home to infect their families, while she was studying kids infected with the virus (and later published the study) without notifying their parents, never mind getting their permission first. Heil Hitler, Dear Evil Bonnie!
Study is part of the RECOVER consortium with over 1 million kids.
Children and adolescents with SARS-COV-2 infection had higher risk of heart failure, chest pain, myocarditis, cardiac arrest, among others. Nearly double the risk of any outcome with infection.
Earlier studies also show behavioral and neurological changes associated with infection in children.
Children are at high risk for Long COVID simply because they have a longer life span to be reinfected multiple times. Vaccination and other protective measures (e.g. ventilation, filtration) are critical.
There are safe and effective vaccines, including the novavax option that is much less reactogenic (fewer side effects) and just as effective, if not more effective, in adolescents
Finally, protecting yourself from covid not only reduces your own chance of long COVID, but also helps protect those around you, including children. There are societal benefits both now and also for future generations.
- Bingyu Zhang,
- Deepika Thacker,
- Ting Zhou,
- Dazheng Zhang,
- Yuqing Lei,
- Jiajie Chen,
- Elizabeth A. Chrischilles,
- Dimitri A. Christakis,
- Soledad Fernandez,
- Vidu Garg,
- Susan Kim,
- Abu S. M. Mosa,
- Marion R. Sills,
- Bradley W. Taylor,
- David A. Williams,
- Qiong Wu,
- Christopher B. Forrest &
- Yong Chen
April 11, 2025, Nature Communications volume 16, Article number: 3445 (2025)
Abstract
The risk of cardiovascular outcomes following SARS-CoV-2 infection has been reported in adults, but evidence in children and adolescents is limited. This paper assessed the risk of a multitude of cardiac signs, symptoms, and conditions 28-179 days after infection, with outcomes stratified by the presence of congenital heart defects (CHDs), using electronic health records (EHR) data from 19 children’s hospitals and health institutions from the United States within the RECOVER consortium between March 2020 and September 2023. The cohort included 297,920 SARS-CoV-2-positive individuals and 915,402 SARS-CoV-2-negative controls. Every individual had at least a six-month follow-up after cohort entry. Here we show that children and adolescents with prior SARS-CoV-2 infection are at a statistically significant increased risk of various cardiovascular outcomes, including hypertension, ventricular arrhythmias, myocarditis, heart failure, cardiomyopathy, cardiac arrest, thromboembolism, chest pain, and palpitations, compared to uninfected controls. These findings were consistent among patients with and without CHDs. Awareness of the heightened risk of cardiovascular disorders after SARS-CoV-2 infection can lead to timely referrals, diagnostic evaluations, and management to mitigate long-term cardiovascular complications in children and adolescents.
@tthiking:
wow that is not good.
2025:
@atranscendedman:
Kyoto University researchers reviewed data linking all seven known human coronaviruses to neurological damage.
Finding is that some coronaviruses, especially SARS-CoV-2, may worsen or trigger neurodegenerative diseases by mimicking amyloid proteins.
Neurotoxic Implications of Human Coronaviruses in Neurodegenerative Diseases: A Perspective from Amyloid Aggregation by Thi Hong Van Nguyen, Francois Ferron, and Kazuma Murakami, April 24, 2025, American Chemical Society
https://doi.org/10.1021/acschembio.5c00153
Abstract
Human coronaviruses (HCoVs) include seven species: HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV, SARS-CoV-1, and SARS-CoV-2. The last three, classified as Betacoronaviruses, are highly transmissible and have caused severe pandemics. HCoV infections primarily affect the respiratory system, leading to symptoms such as dry cough, fever, and breath shortness, which can progress to acute respiratory failure and death. Beyond respiratory effects, increasing evidence links HCoVs to neurological dysfunction. However, distinguishing direct neural complications from preexisting disorders, particularly in the elderly, remains challenging. This study examines the association between HCoVs and neurodegenerative diseases like Alzheimer disease, Parkinson disease, Lewy body dementia, amyotrophic lateral sclerosis, and Creutzfeldt-Jakob disease. It also presents the long-term neurological effects of HCoV infections and their differential impact across age groups and sexes. A key aspect of this study is the investigation of the sequence and structural similarities between amyloidogenic and HCoV spike proteins, which can provide insights into potential neuropathomechanisms.
2023:
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