Endocrine complications of COVID-19: diabetes, musculoskeletal, thyroid, pituitary, adrenal, and gonadal disorders

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social:

No organ or system this virus cannot access and destroy ☠️

Endocrine complications of COVID-19: diabetes, musculoskeletal, thyroid, pituitary, adrenal, and gonadal disorders by Kamyar Asadipooya and Srividya Sriramula, Sept 25, 2026, Journal of the Endocrine Society, Volume 10, Issue 10, October 2026, bvag219, https://doi.org/10.1210/jendso/bvag219

Abstract

COVID-19 is generally associated with both short- and long-term complications. It can affect multiple organ systems and lead to severe or prolonged organ dysfunction, including the endocrine system. It also places a substantial burden on individuals and the health-care system. Therefore, providing up-to-date information for health-care providers is valuable. In this review, we aim to consolidate the current literature regarding the endocrine complications of acute SARS-CoV-2 infection, with a particular focus on diabetes, calcium homeostasis, pituitary, thyroid, adrenal, and gonadal disorders. Although current therapeutic approaches for COVID-19 are mainly limited to antivirals, symptomatic therapies, and supportive care, advances in understanding the mechanisms of SARS-CoV-2 entry and immune responses may support a more effective and personalized approach to clinical care.

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